Flavonoids in Grape serves as a potent anti oxidant that works as a cancer preventative, can inhibit the oxidation of LDL in the coronary vessel wall, has antimicrobial effects, improve endothelial function, inhibit atherosclerosis (fatty deposits in blood vessels).
Quercetin is a phytochemical that include flavonoids, have anti oxidant activity, inhibiting protein kinases and DNA topoisomerases, regulate gene expression, also modulate the expression of genes associated with oxidative stress and anti oxidant defense system.
Quercetin is able to change the expression of cell cycle regulators and apoptotic proteins so as to effectively prevent prostate cancer, mutation of the p53 protein and inhibits the G2-M phase so as to effectively prevent breast cancer, inhibits cell differentiation so that either prevent malignancy of colorectal (colon and rectum), also play a role in the phase G2 / M, so the potential to treat leukemia. Further research is needed on these findings.
Polyphenols are also anti oxidants. In grapes known as resveratrol, inhibits the function of enzymes and stimulates the growth of cancer cells suppress the immune system.
In fact, resveratrol has been known for centuries in Asian medical world as Ko-jo-cone, in the form of flour / powdered root of Polygonum cuspidatum, as anti inflammatory drugs. Interestingly, resveratrol in grape skin serves as a powerful anti oxidant, take place protective against ischemia reperfusion events (lack of blood supply), especially in skeletal muscle (skeleton) rats.
Resveratrol can suppress NF-kB activation and pr-downregulate various gene products trigger inflammation, such as COX-2, 5-LOX, IL-1b, and IL-6, which all play an important role in the occurrence of inflammation of the joints (arthritis). This shows the role of preventive therapy for arthritis as well.
Resveratrol also has an effect so as to prevent anti proliferasi histiositik lymphoma and cancers of the colon (large intestine), alters gene expression in the androgen axis and cell cycle regulation so as to effectively prevent prostate cancer.
The components on the anti microbial effect of wine, such as gallic acid, hydroxycinnamic acids, flavanols, flavonols, trans-resveratrol, and tannin.
Other compounds also multi-nutrient. Saponin (15 mg / day) can lower blood sugar levels, inhibit and prevent the absorption of cholesterol in the blood. Ellagic acid helps slow down the development of tumors.
Magnesium launched a bowel movement. Manganese helps stabilize blood sugar, play a role in the metabolism of fat, connective tissue and bone formation. Proanthocyanidine can prevent strokes, heart attacks, and fight the aging process.
Choose grapes that are still fused with the stem, the same size and uniform, intact, its surface smooth, not dry stalks. To be durable and long lasting, wine should be stored in the refrigerator. Wash with soap before eating a special fruit. Eat with the skin because it is rich in flavonoids.
In order to maintain stamina and health, as well as remove toxins in the body, drink grape juice or eat fresh grapes every day for a week in a row. Hemm … Apparently, in addition to delicious and healthy, the wine is also multi-nutrient. Want to try?